News Summary
The Indianapolis Colts will face the Los Angeles Rams in a crucial Week 4 matchup. The Colts, currently undefeated, look to extend their winning streak, while the Rams seek redemption. Key injuries and strong performances from both teams could influence the game’s outcome, making it a significant contest early in the NFL season.
Indianapolis, IN —
The Indianapolis Colts have traveled nearly 2,000 miles to face the Los Angeles Rams in a highly anticipated Week 4 matchup, with both teams eager to improve their standings early in the 2025 NFL season. The Colts look to continue their winning streak and extend their consecutive wins to four, while the Rams aim to rebound after a challenging start to the season.
Colts’ Season Overview and Key Players
With an undefeated record so far, the Colts have made a strong statement in the AFC South. They are currently leading the division early in the season, thanks in large part to the effective restructuring under head coach Shane Steichen. The team’s offensive play has been notably efficient, averaging 34.2 points per game, led by quarterback Daniel Jones, whose performance has been instrumental to their success.
Jones has demonstrated strong leadership and accurate passing, helping the team secure three consecutive victories. These early wins are a positive sign for the Colts as they look to maintain momentum against a tough Rams squad.
Injury Updates and Rotations
One notable injury concern for the Colts involves Alec Pierce, who has entered concussion protocol. This development has led to Mitchell, a second-year receiver, being slotted as the third starting receiver for the upcoming game. Mitchell has seen limited action this season, with only four catches accumulating 41 yards thus far. Despite this, there is optimism that Mitchell might exploit defensive gaps to score his first career touchdown in this match.
Defensive back Julian Ward has been limited to only two games this season due to a concussion. His recent return against the Tennessee Titans was impactful, as he successfully limited Calvin Ridley to just one catch for 27 yards. Ward’s presence is considered crucial for bolstering the Colts’ secondary in this critical game.
Defensive and Defensive Line Performance
Linebacker Latu has emerged as the top-rated pass rusher according to Pro Football Focus, yet he has yet to record a sack this season. His previous performances have shown improvement, and he is eager to translate his efforts into actual sacks to increase his contribution to the team’s defensive strength.
Matchup Details and Predictions
The game is scheduled to kick off at 4:05 p.m. ET at SoFi Stadium, with the Rams listed as 3.5-point favorites. This game presents a critical test for the undefeated Colts, who will face a Rams team known for its recent ups and downs. The Rams, for instance, lost a game after holding a 19-point lead against the Philadelphia Eagles earlier this season.
Both teams will be assessing their performances against a significant opponent, with the Colts aiming to extend their winning streak and the Rams seeking a redemption victory. The Rams’ quarterback, Matthew Stafford, has thrown an interception in each of his last two games, an area the team will want to improve on heading into this matchup.
Overall, the game is expected to be a competitive contest, testing both teams’ offensive capabilities and defensive resilience. As the Colts look to maintain their strong offensive form, they’ll need to contend with the Rams’ tough defense and improve execution to secure their fourth straight win.
Additional Context
This upcoming game marks the second straight road game for the Colts, who are aiming to continue their momentum despite the challenges posed by travel and opposing team strength. Both teams are analyzing recent performances, with the Colts focusing on their offensive efficiency and the Rams working to bolster their defense against high-powered offenses.
Summary
The Colts are seeking a fourth consecutive victory in their Week 4 game against the Los Angeles Rams at SoFi Stadium, with kickoff scheduled for 4:05 p.m. ET. The matchup features key players returning from injury, a strong offensive showing from the Colts, and a Rams team looking to bounce back after recent setbacks. The game is expected to be a pivotal moment early in the NFL season for both teams, with implications for division standings and playoff aspirations.
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Additional Resources
- IndyStar: NFL Week 4 Predictions
- Los Angeles Rams: Game Trailer
- USA Today: Rams vs. Colts Best Bets
- Wikipedia: Indianapolis Colts
- Sports Illustrated: Colts Bold Predictions
- Google Search: 2025 NFL Week 4 Colts vs Rams

Author: STAFF HERE INDIANAPOLIS WRITER
The INDIANAPOLIS STAFF WRITER represents the experienced team at HEREIndianapolis.com, your go-to source for actionable local news and information in Indianapolis, Marion County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as the Indianapolis 500, Indy Jazz Fest, and the Indiana State Fair. Our coverage extends to key organizations like the Indy Chamber and Visit Indy, plus leading businesses in motorsports and healthcare that power the local economy such as Indianapolis Motor Speedway and IU Health. As part of the broader HERE network, we provide comprehensive, credible insights into Indiana's dynamic landscape.


